Publications
2026
Rossi V., Masi M., Govoni M., Veronesi M., Duca M., Girotto S., Cavalli A., Di Stefano G.
A Metabolites’ Interplay Can Modulate DNA Repair by Homologous Recombination
International Journal of Molecular Sciences, vol. 27, (no. 3)
2026
Milordini G., Zacco E., Masi M., Armaos A., Di Palma F., Oneto M., Gilodi M., Rupert J., Broglia L., Varignani G., Scotto M., Marotta R., Girotto S., Cavalli A., Tartaglia G.G.
Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality
Nature Communications, vol. 17, (no. 1)
2026
Cianci F., Verduci I., Cazzoli R., Cannavale G., Rey G., Veronesi M., Balboni B., Ranucci M., Palloni L.M.G., Ballabio F., Barsotti N., Ailuno G., Balboni A., Baldassari S., Caviglioli G., Tacconi C., Camilloni C., Girotto S., Fantin A., Barbieri F., Cavalli A., Pasqualetti M., Florio T., Minucci S., Mazzanti M.
Correction: Chronic administration of metformin exerts cytostatic and cytotoxic effects via the PP2A-GSK3β-MCL-1 pathway by inhibiting the tmCLIC1 membrane protein in glioblastoma-initiating cells (Journal of Experimental & Clinical Cancer Research, (2025), 44, 1, (312), 10.1186/s13046-025-03577-3)
Journal of Experimental and Clinical Cancer Research, vol. 45, (no. 1)
2026
Rinaldi F., Franco P., Langer J. D., Girotto S., Cavalli A.
Decoding the RAD51–BRC repeats interplay in Homologous Recombination
BMM-AIC Structural Biology Meeting 2026
Poster
Conference
2026
Ferrandi G., Bagnolini G., Poppi L., Masi M., Previtali V., Andonaia A., Varignani G., Veronesi M., De Franco F., Falchi F., Di Stefano G., Girotto S., Roberti M., Cavalli A.
Targeting RAD51-BRCA2 Interaction to Enhance Synthetic Lethality with Olaparib in Pancreatic Cancer: Development of a Novel Phenyl Furan-Quinoline-Carboxylic Acid Series
ACS Medicinal Chemistry Letters, vol. 17, (no. 2), pp. 520-530
2025
Rinaldi F., Balboni B., Varignani G., Milordini G., Marotta R., Girotto S., Cavalli A.
An integrative structural study of RAD52, an emerging target in anticancer drug discovery
XXIX National Meeting on Medicinal Chemistry of the Italian Chemistry Society
Poster
Conference
2025
Rinaldi F., Balboni B., Girotto S., Cavalli A.
An integrative structural study of RAD52, an emerging target in anticancer drug discovery
XXIX National Meeting on Medicinal Chemistry of the Italian Chemistry Society
Poster
Conference
2025
Rinaldi F., Franco P., Veronesi M., Romeo E., Bresciani V., Varignani G., Catalano F., Bernetti M., Masetti M., Langer J. D., Girotto S., Cavalli A.
Breaking new ground into RAD51–BRC repeats interplay in Homologous Recombination
Research Square
Article
E-print Archive
2025
Cianci F., Verduci I., Cazzoli R., Cannavale G., Rey G., Veronesi M., Balboni B., Ranucci M., Palloni L.M.G., Ballabio F., Barsotti N., Ailuno G., Balboni A., Baldassari S., Caviglioli G., Tacconi C., Camilloni C., Girotto S., Barbieri F., Fantin A., Cavalli A., Pasqualetti M., Florio T., Minucci S., Mazzanti M.
Chronic administration of metformin exerts cytostatic and cytotoxic effects via the PP2A-GSK3β-MCL-1 pathway by inhibiting the tmCLIC1 membrane protein in glioblastoma-initiating cells
Journal of Experimental and Clinical Cancer Research, vol. 44, (no. 1)
2025
Milordini G., Zacco E., Armaos A., Di Palma F., Masi M., Gilodi M., Rupert J., Broglia L., Varignani G., Oneto M., Scotto M., Marotta R., Girotto S., Cavalli A., Tartaglia G.G.
Computationally-designed aptamers targeting RAD51-BRCA2 interaction inhibit RAD51 nuclear recruitment
bioRxiv
2025
Torielli L., Castelli M., Milani F., Heritz J.A., Cayaban S.J., Hernandez J., Serapian S.A., Magni A., Frasnetti E., Doria F., Pirota V., Wengert L.A., Woodford M.R., Lodigiani G., Bergamaschi G., Veronesi M., Bandiera T., Girotto S., Paladino A., Prodromou C., Backe S.J., Bourboulia D., Canciani A., Arrigoni C., Lolicato M., Gestwicki J.E., Mollapour M., Colombo G.
Design of multi-target peptide modulators for protein chaperone networks
Structure
2025
Quaia R., Veronesi M., Anselmi M., Russo D., Penna I., Scarpelli R., Girotto S., Bertozzi F., Duca M., Bandiera T.
Development of fluorinated fragments into novel modulators of micro-RNA-21 levels
European School of Medicinal Chemistry – 44th Edition
Poster
Conference
2025
Anselmi M., Russo D., Penna I., Quaia R., Panosetti M., Scarpelli R., Girotto S., Veronesi M., Bertozzi F., Duca M., Bandiera T.
DISCOVERY OF NOVEL SMALL-MOLECULE MODULATORS OF microRNA-21 IN PANCREATIC CANCER CELLS
59th International Conference on Medicinal Chemistry
Poster
Conference
2025
Bresciani V., Rinaldi F., Franco P., Girotto S., Cavalli A., Langer J. D., Masetti M., Bernetti M.
Dissecting the RAD51-BRC4 Interaction Landscape through Integrative Molecular Simulations and Experimental Biophysics
Journal of Chemical Information and Modeling
Article
Journal
2025
Bresciani V., Rinaldi F., Franco P., Girotto S., Cavalli A., Langer J.D., Masetti M., Bernetti M.
Dissecting the RAD51–BRC4 Interaction Landscape through Integrative Molecular Simulations and Experimental Biophysics
Journal of Chemical Information and Modeling, vol. 65, (no. 21), pp. 11965-11978
2025
Rinaldi F., Balboni B., Marotta R., Girotto S., Cavalli A.
Elucidating RAD52 architecture through an integrated structural biology approach
51st Meeting of the Italian Crystallographic Association
Poster
Conference
2025
Quatraccioni M., Ocello R., Falchi F., Previtali V., Veronesi M., Varignani G., Margaroli N., Masi M., Scarpelli R., Girotto S., Cavalli A.
In search of small molecules targeting RAD52 for synthetic lethality (P120)- September 14-17, 2025, Parma (Italy)
XXIX National Meeting on Medicinal Chemistry
Poster
Conference
2025
Bresciani V., Rinaldi F., Franco P., Girotto S., Cavalli A., Langer J. D., Masetti M., Bernetti M.
Integrating computational and experimental biophysics reveals novel insights into the RAD51-BRC4 interaction
BiorXiv