Publications
2026
Rinaldi F., Veronesi M., Masi M., Andonaia A., Varignani G., Catalano F., Marotta R., Girotto S., Cavalli A.
A chemical biology probe identified through 19F-NMR induces RAD51 polymerization and perturbs BRC4 engagement
EMBO Workshop Chemical biology 2026
Poster
Conference
2026
Rinaldi F., Veronesi M., Masi M., Andonaia A., Bosio S., Varignani G., Catalano F., Marotta R., Falchi F., Girotto S., Cavalli A.
A chemical biology probe identified through 19F NMR screening stimulates RAD51 oligomerization and disrupts BRC4 binding
Division of Chemistry of Biological Systems Italian Chemical Society Conference 2026
Poster
Conference
2026
Rinaldi F., Veronesi M., Andonaia A., Varignani G., Marotta R., Girotto S., Cavalli A.
A fragment identified by 19F NMR stabilizes RAD51 fibrils and antagonizes BRC4 binding
50th FEBS Congress
Poster
Conference
2026
Rossi V., Masi M., Govoni M., Veronesi M., Duca M., Girotto S., Cavalli A., Di Stefano G.
A Metabolites’ Interplay Can Modulate DNA Repair by Homologous Recombination
International Journal of Molecular Sciences, vol. 27, (no. 3)
2026
Rinaldi F., Franco P., Langer G., Girotto S., Cavalli A.
An integrated biophysical and structural biology approach to investigate the BRCA2-RAD51 interaction
FEBS Advanced Course 'Lost in Integration Vol. 2 - Probing biomolecules with AI and experiments'
Poster
Conference
2026
Rinaldi F., Franco P., Langer J., Girotto S., Cavalli A.
An Integrative Structural Mapping of the RAD51 BRC Repeats Interfaces
EMBO Workshop: The DNA damage response in cell physiology and diseases
Poster
Conference
2026
Demuro S., Russo D., Penna I., Grabska S., Grabski H., Dalle Vedove A., Valeri A., Sauvey C., Ottonello G., Summa M., Bertozzi S.M., Ortega J., Bertorelli R., Storici P., Girotto S., Cruciani G., Di Martino R.M.C., Abagyan R., Cavalli A.
A Polypharmacology-Driven Approach to Alzheimer’s Disease and Tauopathies: Rational Design, Synthesis and Characterization of Amino-Pyrazole-Based Multikinase (GSK-3β/FYN-α/DYRK1A) Inhibitors
Journal of Medicinal Chemistry, vol. 69, (no. 9), pp. 9991-10018
2026
Servoli F., Giaimo M., Pierini V., Bardelli V., Arniani S., Lucarelli M., Matteucci C., Crescenzi B., Romoli S., Pagliaro L., Zamponi R., Fiou A., Vecchi M., Landuzzi F., Forghieri F., Curti A., Cambo B., Pasciolla C., Lessi F., Lussana F., Cavalli A., Roti G., Martelli M.P., Starza R.L.
BIALLELIC LOSS OF RB1 AND LPAR6 AT 13Q14 DRIVES KEY CELL CYCLE ABNORMALITIES IN T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Haematologica, vol. 111
2026
Milordini G., Zacco E., Masi M., Armaos A., Di Palma F., Oneto M., Gilodi M., Rupert J., Broglia L., Varignani G., Scotto M., Marotta R., Girotto S., Cavalli A., Tartaglia G.G.
Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality
Nature Communications, vol. 17, (no. 1)
2026
Cianci F., Verduci I., Cazzoli R., Cannavale G., Rey G., Veronesi M., Balboni B., Ranucci M., Palloni L.M.G., Ballabio F., Barsotti N., Ailuno G., Balboni A., Baldassari S., Caviglioli G., Tacconi C., Camilloni C., Girotto S., Fantin A., Barbieri F., Cavalli A., Pasqualetti M., Florio T., Minucci S., Mazzanti M.
Correction: Chronic administration of metformin exerts cytostatic and cytotoxic effects via the PP2A-GSK3β-MCL-1 pathway by inhibiting the tmCLIC1 membrane protein in glioblastoma-initiating cells (Journal of Experimental & Clinical Cancer Research, (2025), 44, 1, (312), 10.1186/s13046-025-03577-3)
Journal of Experimental and Clinical Cancer Research, vol. 45, (no. 1)
2026
Aguti R., Bernetti M., Elisi G.M., Cavalli A., Masetti M.
Critical Assessment of a Structure-Based Pipeline for Targeting the Long Noncoding RNA MALAT1
Journal of Chemical Information and Modeling, vol. 66, (no. 7), pp. 4187-4201
2026
Rinaldi F., Franco P., Langer J. D., Girotto S., Cavalli A.
Decoding the RAD51–BRC repeats interplay in Homologous Recombination
BMM-AIC Structural Biology Meeting 2026
Poster
Conference
2026
Masi M., Varignani G., Cavalli A., Girotto S.
Expanding Synthetic Lethality in DNA Damage Response-Defective Cancers Through Stress Phenotype-Guided Kinase Targeting
International Journal of Molecular Sciences, vol. 27, (no. 18)
2026
Bosio S., Freccia A., Masi M., Rinaldi F., Girotto S., Falchi F., Cavalli A.
Exploring RAD51 structural plasticity through molecular simulations and integrative structural biology
25th European Symposium on Quantitative Structure-Activity Relationship
Poster
Conference
2026
Marangoni S., Furia F., Charrance D., Fant A., Di Dio S., Trova S., Spirito G., Musacchia F., Coppe A., Gustincich S., Vecchi M., Landuzzi F., Cavalli A.
GeNePi: a graphics processing unit enhanced next-generation bioinformatics pipeline for whole-genome sequencing analysis
Briefings in Bioinformatics, vol. 27, (no. 1)
2026
Bassi P.R.A.S., Li W., Chen J., Zhu Z., Lin T., Decherchi S., Cavalli A., Wang K., Yang Y., Yuille A.L., Zhou Z.
Learning Segmentation from Radiology Reports
Lecture Notes in Computer Science, vol. 15964 LNCS, pp. 305-315
2026
Lantieri F., Croci S., Decherchi S., Rusmini M., Recchi G., Bonacini M., Ferrigno I., Rossi A., Castillo De Spelorzi Y.C., Henzen E., Rosamilia F., Cangelosi D., Landuzzi F., Angius A., Rallo V., Mancuso P., Pezzarossi A., Giorgi Rossi P., Catanoso M., Gattorno M., Cavalli A., Meroni P.L., Vozzi D., Uva P., Ceccherini I., Salvarani C.
Machine learning, whole genome sequencing, and Mendelian randomization support a role of CRP on COVID-19 severity
Molecular Medicine, vol. 32, (no. 1)
2026
Rinaldi F., Franco P., Langer J. D., Girotto S., Cavalli A.
Molecular determinants of the BRC Repeats - RAD51 recognition
12th International Conference on Biological Physics
Poster
Conference